1. Pleiotropic cytotoxicity of VacA toxin in host cells and its impact on immunotherapy

Farnaz Fahimi, Mohammad Reza Tohidkia, Mehdi Fouladi, Reza Aghabeygi, Naser Samadi, Yadollah Omidi*

Bioimpacts. 2017;7(1): 59-71. doi: 10.15171/bi.2017.08

PMCID: PMC5439391 PMID: 28546954 Scopus ID: 85019068034

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Original Research

2. Lactobacillus plantarum induces apoptosis in gastric cancer cells via modulation of signaling pathways in Helicobacter pylori

Hadi Maleki-Kakelar , Jaber Dehghani, Abolfazl Barzegari, Jaleh Barar , Masoud Shirmohamadi, Javid Sadeghi, Yadollah Omidi*

Bioimpacts. 2020;10(2): 65-72. doi: 10.34172/bi.2020.09

PMCID: PMC7186545 PMID: 32363150 Scopus ID: 85088607061

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Based on in vitro experiments, the anti-cancer effect of the locally isolated L. plantarum was validated through some signaling pathways, including PTEN, Bax, TLR4, and AKT genes.

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